With a diagnosis of Chalazion, it is important to consider whether there is an underlying condition causing the Chalazion.

There are other medical conditions that may possibly cause Chalazion. A chalazion is usually secondary to some local inflammation or local infection such as a stye. It may be due to a residual aggregation of inflammatory cells following an eyelid infection such as hordeola and preseptal cellulitis, or may develop from the retention of meibomian gland secretions.

Cases of recurrent chalazia are frequently due to chronic blepharitis or poor lid hygiene.

All of the above ultimately lead to inflammation of the meibomian gland and this causes blockage of the duct which drains the gland.Duct blockage causes chronic enlargement of the gland and this presents as chalazion.